CD44 Monoclonal Antibody (KM201), FITC, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-113-7690-Each-of-1 | In Stock | ₹ 28,747.00 |
50-113-7690 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,747.00
GST (18%): ₹ 5,174.46
Total Price: ₹ 33,921.46
Antigen
CD44
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with <0.1% sodium azide
Gene Accession No.
P15379
Gene Symbols
CD44
Immunogen
(C57 BL/6 x DBA/2)F1 mouse bone marrow derived stromal cells clone BM52.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
KM201
Conjugate
FITC
Gene
CD44
Gene Alias
AU023126; AW121933; AW146109; Bovine CD44; CD44; CD44 antigen; CD44 antigen-like protein; CD44 molecule; CD44 molecule (Indian blood group); CD44 protein; CD44 variant; CD44A; CD44-like protein; CDW44; cell surface glycoprotein CD44; Cell surface glycoprotein CD44 (hyaluronate binding protein); cell-surface glycoprotein; chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; Epican; extracellular matrix receptor III; extracellular matrix receptor-III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCH-I; hyaluronan receptor; Hyaluronate receptor; IN; LHR; Ly-24; lymphocyte antigen 24; lymphocyte surface antigen precursor CD44; MC56; MDU2; MDU3; METAA; MIC4; PGP I; Pgp1; PGP-1; PGPI; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; putative Bos taurus CD44; RHAMM; sCD 44; sCD44; soluble CD 44; soluble CD44
Host Species
Rat
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
12505
Content And Storage
4° C, store in dark
Form
Liquid
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Description
- CD44 cell surface antigen is a 100 kDa type 1 transmembrane glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast
- Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues
- CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration
- CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing
- CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential
- CD44 is expressed by hematopoietic, non-hematopoietic cells, epithelial tissues, and to filopodia in cultured keratinocytes
- Further, bone marrow myeloid cells and memory T cells express CD44 at high levels, and peripheral B and T cells can upregulate the expression of CD44 in response to certain stimulatory events
- Transcripts for the CD44 gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full-length nature of some of these variants have not been determined
- Alternative splicing is the basis for the structural and functional diversity of the CD44 protein
- Diseases associated with CD44 dysfunction include superficial keratitis and lichen sclerosus
- CD44 also may be related to tumor metastasis formation.