CD74 Monoclonal Antibody (LN2), FITC, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-113-7723-Each-of-1 | In Stock | ₹ 20,470.00 |
50-113-7723 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 20,470.00
GST (18%): ₹ 3,684.60
Total Price: ₹ 24,154.60
Antigen
CD74
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with <0.1% sodium azide
Gene Accession No.
P04233
Gene Symbols
CD74
Immunogen
Human CD74 from Cell line SU-DHL-4 nuclei
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
LN2
Conjugate
FITC
Gene
CD74
Gene Alias
CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; DHLAG; dinucleotide microsatellite; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; Ii; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; MHC class II-associated invariant chain; MHC HLA-DR gamma chain; p33
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
972
Content And Storage
4° C, store in dark
Form
Liquid
Related Products
Description
- HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB)
- The alpha chain gene contains 5 exons
- Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail
- DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5
- Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
- Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
- HLA-DR is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes
- Three loci, DR, DQ and DP, encode the major expressed products of the human class II region
- The human MHC class II molecules bind intracellularly processed peptides, present them to T-helper cells, and have a critical role in the initiation of the immune response.