50-122-07

GM-CSF Monoclonal Antibody (MP1-31G6), Biotin, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-122-07-Each-of-1 In Stock ₹ 15,041.00

50-122-07 - Each of 1

₹ 15,041.00

In Stock

Quantity

1

Base Price: ₹ 15,041.00

GST (18%): ₹ 2,707.38

Total Price: ₹ 17,748.38

Antigen

GM-CSF

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P01587

Gene Symbols

CSF2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12981

Content And Storage

4° C, do not freeze

Form

Liquid

Applications

ELISA

Clone

MP1-31G6

Conjugate

Biotin

Gene

CSF2

Gene Alias

colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim

Host Species

Rat

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The MP1-31G6 antibody reacts with mouse granulocyte/macrophage - colony stimulating factor (GM-CSF), a 14 kDa cytokine secreted by activated T cells and macrophages
  • Applications Reported: MP1-31G6 has been reported for use in detection of mouse GM-CSF by ELISA
  • Applications Tested: The MP1-31G6 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of mouse GM-CSF (Granulocyte/Macrophage-Colony Stimulating Factor, GMCSF) in combination with the purified MP1-22E9 (14-7331) antibody for capture and recombinant mouse GM-CSF (14-8331) as the standard
  • A suitable range of concentrations of this antibody for ELISA detection is 0.5-2 μg/mL
  • A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate
  • Filtration: 0.2 μm post-manufacturing filtered
  • The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes
  • The active form of the protein exists as a homodimer in the extracellular space
  • This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia
  • Other genes in the cluster include interleukins 4, 5, and 13
  • The gene is involved in promoting tissue inflammation
  • Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome
  • Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.