CD309 (FLK1) Monoclonal Antibody (Avas12a1), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-131-85-Each-of-1 | In Stock | ₹ 12,282.00 |
50-131-85 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,282.00
GST (18%): ₹ 2,210.76
Total Price: ₹ 14,492.76
Antigen
CD309 (FLK1)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P35918
Gene Symbols
KDR
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16542
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry, Western Blot
Clone
Avas12a1
Conjugate
Unconjugated
Gene
KDR
Gene Alias
6130401C07; CD309; CD309 antigen; fetal liver kinase 1; fetal liver kinase-1; FLK1; Flk-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); flk-1 type VEGF receptor; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; vascular endotheial growth factor 2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The Avas12a1 monoclonal antibody reacts with mouse Flk-1, also known as vascular endothelial growth factor receptor 2 (VEGFR2)
- Flk-1 is a receptor tyrosine kinase involved in vascular endothelial tissue development and is expressed on endothelial cells during embryonic stages and some endothelial tissues in the adult
- Applications Reported: The Avas12a1 antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), and immunohistochemical staining
- Applications Tested: This Avas12a1 antibody has been tested by flow cytometric analysis of bEnd.3 cells
- This can be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase
- It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors
- FLK1 (VEGF Receptor 2) encodes one of the two receptors of the VEGF
- This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase
- The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc
- Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.