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50-138-14

CD321 (F11R) Monoclonal Antibody (WK9), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-138-14-Each-of-1 In Stock ₹ 22,695.00

50-138-14 - Each of 1

₹ 22,695.00

In Stock

Quantity

1

Base Price: ₹ 22,695.00

GST (18%): ₹ 4,085.10

Total Price: ₹ 26,780.10

Antigen

CD321 (F11R)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q9Y624

Gene Symbols

F11r

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

50848

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

WK9

Conjugate

Unconjugated

Gene

F11r

Gene Alias

9130004G24; AA638916; BV11 antigen; CD321; ESTM33; F11 R; F11 receptor; F11 receptor/F11R; F11R; JAM; JAM1; JAM-1; JAMA; JAM-A; Jcam; Jcam1; junction cell adhesion molecule A; junction cell adhesion molecule1; junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; Ly106; PAM-1; Platelet adhesion molecule 1; platelet F11 receptor; UNQ264/PRO301

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Description

  • Description: CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors
  • CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail
  • The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins
  • CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, epithelial and endothelial cells, and plays a role in mediating cell-cell contact
  • CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin
  • CD321 is also involved in reovirus entry into cells
  • Applications Reported: This WK9 antibody has been reported for use in flow cytometric analysis and immunoprecipitation
  • The WK9 antibody has also been found useful for immunoblotting, recognizing a protein of approximately 38 kD under reducing and non-reducing conditions
  • Applications Tested: This WK9 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors
  • CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail
  • The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins
  • CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact
  • CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin
  • CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.