Home Products Antibodies Primary Antibodies 50 146 50
50-146-50

MHC Class I (H-2Kd) Monoclonal Antibody (SF1-1.1.1), Functional Grade, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-146-50-Each-of-1 In Stock ₹ 20,559.00

50-146-50 - Each of 1

₹ 20,559.00

In Stock

Quantity

1

Base Price: ₹ 20,559.00

GST (18%): ₹ 3,700.62

Total Price: ₹ 24,259.62

Antigen

MHC Class I (H-2Kd)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.2

Gene Accession No.

P01901, P03991, P04223, P14428

Gene Symbols

H2-K1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14972

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Functional Assay

Clone

SF1-1.1.1

Conjugate

Functional Grade

Gene

H2-K1

Gene Alias

class I major histocompatibility antigen H-2Kd; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2-K1; histocompatibility 2, K1, K region; K-f; MGC184092; MGC7052; MHC class I antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-K transplantation antigen

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Description

  • Description: This SF1-1.1.1 monoclonal antibody reacts with the H-2Kd MHC class I alloantigen
  • H-2Kd is involved in antigen presentation to T cells expressing CD3/TCR and CD8
  • Reactivity to other haplotypes (e.g
  • b, j, k, p, q, s, and v) has not been observed
  • This monoclonal antibody has been reported to block CD8 involvement in TCR-ligand binding
  • Applications Reported: This SF1-1.1.1 antibody has been reported for use in functional assays
  • Applications Tested: This SF1-1.1.1 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 0.125 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Storage and handling: Use in a sterile environment
  • Filtration: 0.2 μm post-manufacturing filtered
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay
  • Aggregation: Less than 10%, as determined by HPLC
  • This protein is an MHC class I alloantigen, which is involved in antigen presentation to T cells expressing CD3/TCR and CD8
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.