50-155-6765
RFX5 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-6765-Each-of-1 | In Stock | ₹ 43,546.81 |
50-155-6765 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,546.81
GST (18%): ₹ 7,838.426
Total Price: ₹ 51,385.236
Antigen
RFX5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RFX5
Gene Alias
RP11-126K1.5
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5993
Content And Storage
4° C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
P48382
Gene Symbols
RFX5
Immunogen
Between 575 and C-term
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920)
- At least 4 complementation groups have been identified in B-cell lines established from patients with BLS
- The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters
- The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995)
- RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif
- Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined.