50-155-6809
SMC1 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-6809-Each-of-1 | In Stock | ₹ 43,546.81 |
50-155-6809 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,546.81
GST (18%): ₹ 7,838.426
Total Price: ₹ 51,385.236
Antigen
SMC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMC1A
Gene Alias
RP6-29D12.1, CDLS2, DKFZp686L19178, DXS423E, KIAA0178, MGC138332, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
24061, 8243
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
Q14683, Q9CU62
Gene Symbols
SMC1A
Immunogen
Between 1175 and C-term
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine Structural Maintece of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression
- The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregatior defects
- This suggests a critical function of SMC family proteins in mitotic chromosome dynamics
- SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells
- Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase
- Mutations in the gene can lead to Cornelia de Lange syndrome 2.