50-155-7265
PCNA Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-7265-Each-of-1 | In Stock | ₹ 43,546.81 |
50-155-7265 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,546.81
GST (18%): ₹ 7,838.426
Total Price: ₹ 51,385.236
Antigen
PCNA
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PCNA
Gene Alias
ATLD2, cyclin, DNA polymerase delta auxiliary protein, PCNA
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18538, 5111
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
P12004, P17918
Gene Symbols
PCNA
Immunogen
Between 75 and 125
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Chicken and Bovine PCNA (polymerase delta auxiliary protein) is essential for DNA replication and is involved in DNA excision and mismatch repair pathways
- PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT)
- PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumor tissue (i.e
- relevant to prognosis)
- PCNA is a marker for cells in early G1 phase and S phase of the cell cycle
- PCNA is found in the nucleus and is a cofactor of DNA polymerase delta, and acts as a homotrimer and helps increase the processing of leading strand synthesis during DNA replication
- In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway
- Two transcript variants encoding the same protein have been found for PCNA
- Pseudogenes of PCNA have been described on chromosome 4 and on the X chromosome.