50-155-7366
TSC1 Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-7366-Each-of-1 | In Stock | ₹ 12,384.35 |
50-155-7366 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,384.35
GST (18%): ₹ 2,229.183
Total Price: ₹ 14,613.533
Antigen
TSC1
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q92574, Q9EP53
Gene Symbols
TSC1
Immunogen
Between 1100 and C-term
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
TSC1
Gene Alias
Hamartin; Tuberous sclerosis 1 protein; TSC1; KIAA0243; TSC
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
64930, 7248
Content And Storage
4° C
Form
Liquid
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Implicated as a tumor suppressor
- May have a function in vesicular transport
- Interaction between TSC1 and TSC2 may facilitate vesicular docking.Defects in TSC1 are the cause of tuberous sclerosis complex (TSC)
- The molecular basis of TSC is a functional impairement of the hamartin-tuberin complex
- TSC is an autosomal domit multi-system disorder that affects especially the brain, kidneys, heart, and skin
- TSC is characterized by hamartomas (benign overgrowths predomitly of a cell or tissue type that occurs normally in the organ) and hamartias (developmental abnormalities of tissue combination)
- Clinical symptoms can range from benign hypopigmented macules of the skin to profound mental retardation with intractable seizures to premature death from a variety of disease-associated causes.Defects in TSC1 may be a cause of focal cortical dysplasia of Taylor balloon cell type (FCDBC)
- FCDBC is a subtype of cortical displasias linked to chronic intractable epilepsy
- Cortical dysplasias display a broad spectrum of structural changes, which appear to result from changes in proliferation, migration, differentiation, and apoptosis of neuronal precursors and neurons during cortical development.