50-155-7445
PAK4 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-7445-Each-of-1 | In Stock | ₹ 43,546.81 |
50-155-7445 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,546.81
GST (18%): ₹ 7,838.426
Total Price: ₹ 51,385.236
Antigen
PAK4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PAK4
Gene Alias
Serine/threonine-protein kinase PAK 4; p21-activated kinase 4; PAK-4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10298
Content And Storage
4° C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1 mg/ml
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
O96013
Gene Symbols
PAK4
Immunogen
Between 25 and 75
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac
- They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding
- The second group includes PAK4, 5 and 6
- These proteins are not activated by Cdc42/Rac binding
- PAK4 was initially identified as a novel effector of Cdc42Hs
- Co-expression of PAK4 and Cdc42Hs resulted in induction of filopodia and actin polymerization, showing that it is involved in cytoskeletal reorganization
- Other experiments have shown PAK4 to be essential for embryonic viability and proper neuronal development
- PAK4 has also been implicated in anchorage-independent growth of tumor cells and is required for activation of several cancer prosurvival pathways.