50-155-9490
USP20/VDU2 Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-9490-Each-of-1 | In Stock | ₹ 12,384.35 |
50-155-9490 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,384.35
GST (18%): ₹ 2,229.183
Total Price: ₹ 14,613.533
Antigen
USP20/VDU2
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q8C6M1, Q9Y2K6
Gene Symbols
Usp20
Immunogen
Between 863 and 913
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
USP20
Gene Alias
USP20; VDU2; ubiquitin specific protease 20; KIAA1003; pVHL-interacting deubiquitinating enzyme 2; ubiquitin specific peptidase 20; LSFR3A
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10868, 74270
Content And Storage
4° C
Form
Liquid
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling
- Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2)
- Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2
- Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2
- This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins
- Deubiquitinates DIO2, thereby regulating thyroid hormone regulation
- Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity
- Mediates deubiquitination of both ′Lys-48′- and ′Lys-63′-linked polyubiquitin chains.