50-155-9824
CHD8 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-9824-Each-of-1 | In Stock | ₹ 43,546.81 |
50-155-9824 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,546.81
GST (18%): ₹ 7,838.426
Total Price: ₹ 51,385.236
Antigen
CHD8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CHD8
Gene Alias
HELSNF1; KIAA1564
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
57680, 67772
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration
0.2 mg/ml
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q09XV5, Q9HCK8
Gene Symbols
CHD8
Immunogen
Between 2252 and 2302
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- DNA helicase that acts as a chromatin remodeling factor and regulates transcription
- Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes
- Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity
- Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity
- Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes
- Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF
- Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity
- Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.