50-156-2394

Pc2 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-156-2394-Each-of-1 In Stock ₹ 43,546.81

50-156-2394 - Each of 1

₹ 43,546.81

In Stock

Quantity

1

Base Price: ₹ 43,546.81

GST (18%): ₹ 7,838.426

Total Price: ₹ 51,385.236

Antigen

Pc2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CBX4

Gene Alias

E3 SUMO-protein ligase CBX4; Chromobox protein homolog 4; Polycomb 2 homolog; Pc2; hPc2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12418, 8535

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

O00257, O55187

Gene Symbols

CBX4

Immunogen

Between 150 and 200

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • CBX4 is a member of Drosophila Polycomb group gene family
  • The polycomb group (PcG) genes are essential for maintece of proper expression patterns of developmental master regulators; changes in expression pf PcG proteins have been associated with cancer
  • CBX4 is a part of the cellular memory system responsible for the inheritance of gene activity by progeny cells
  • It participates in maintaining the transcriptionally repressive state of genes
  • CBX4 is part of acomplex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ′Lys-119′, rendering chromatin heritably changed in its expressibility
  • CBX4 is an E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I.