50-156-2600
PKN2 Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-2600-Each-of-1 | In Stock | ₹ 12,384.35 |
50-156-2600 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,384.35
GST (18%): ₹ 2,229.183
Total Price: ₹ 14,613.533
Antigen
PKN2
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q16513
Gene Symbols
PKN2
Immunogen
Between 200 and 250
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
PKN2
Gene Alias
RP5-905H16.1, PAK2, PRK2, PRKCL2, PRO2042, Pak-2, cardiolipin-activated protein kinase Pak2; protein kinase C-like 2; protein-kinase C-related kinase 2; serine/threonine-protein kinase N2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5586
Content And Storage
4° C
Form
Liquid
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell
- Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes
- Phosphorylates CTTN in hyaluro-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin
- Phosphorylates HDAC5, therefore lead to impair HDAC5 import
- Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells
- Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner
- Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation
- Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion
- Inhibits Akt pro-survival-induced kinase activity
- Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF)
- Phosphorylates HCV NS5B leading to stimulation of HCV RNA replication.