50-156-2605
PKC-alpha Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-2605-Each-of-1 | In Stock | ₹ 12,384.35 |
50-156-2605 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,384.35
GST (18%): ₹ 2,229.183
Total Price: ₹ 14,613.533
Antigen
PKC-alpha
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PRKCA
Gene Alias
AAG6, aging-associated gene 6, PKCA, PKC-A, PKC-alpha, PRKACA, protein kinase C, alpha
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5578
Content And Storage
4° C
Form
Liquid
Applications
Immunoprecipitation
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
P17252
Gene Symbols
PRKCA
Immunogen
Between 300 and 350
Quantity
10 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat and Rabbit Members of the Protein kinase C (PKC) family of serine/threonine protein kinases are grouped by their activation mechanism
- Classical or conventional PKCs (PKC alpha-, betaI- , betaII- and gamma-) are activated by phosphatidylserine in a calcium dependent manner and can bind diacylglycerol
- The Ca2+ insensitive novel PKCs (PKCs epsilon-, delta-, theta- and eta) are also activated by diacylglycerol and phosphatidylserine
- The atypical PKCs (PKCs iota- and zeta-) are insensitive to Ca2+, DAG and phorbolesters
- All PKCs isoforms consist of a highly conserved catalytic domain connected to a regulatory domain via a hinge region
- PKCs are involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascades involving MAPK1/3 (ERK1/2) and RAP1GAP.