50-157-1419

CENP-B Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-157-1419-Each-of-1 In Stock ₹ 46,161.63

50-157-1419 - Each of 1

₹ 46,161.63

In Stock

Quantity

1

Base Price: ₹ 46,161.63

GST (18%): ₹ 8,309.093

Total Price: ₹ 54,470.723

Antigen

CENP-B

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

P07199

Gene Symbols

CENPB

Immunogen

Between 540 and C-term

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunofluorescence

Conjugate

Unconjugated

Gene

CENPB

Gene Alias

Centromere protein B, 80kDa

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1059

Content And Storage

4° C

Form

Liquid

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • CENPB is a highly conserved protein that facilitates centromere formation
  • It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family
  • It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus
  • It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.This gene product is a highly conserved protein that facilitates centromere formation
  • It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family
  • It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus
  • The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA
  • This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes and is considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.