50-157-1790
CIP2A Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-157-1790-Each-of-1 | In Stock | ₹ 12,384.35 |
50-157-1790 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,384.35
GST (18%): ₹ 2,229.183
Total Price: ₹ 14,613.533
Antigen
CIP2A
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q8TCG1
Gene Symbols
CIP2A
Immunogen
Between 550 and 600
Quantity
10 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunofluorescence, Immunohistochemistry
Conjugate
Unconjugated
Gene
CIP2A
Gene Alias
Cancerous Inhibitor of Protein Phosphatase 2A , p90
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
57650
Content And Storage
4° C
Form
Liquid
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells
- The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation
- In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation
- The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A
- Importantly, CIP2A is overexpressed in two common human maligcies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.