50-157-2131
E2F1 Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-157-2131-Each-of-1 | In Stock | ₹ 46,161.63 |
50-157-2131 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,161.63
GST (18%): ₹ 8,309.093
Total Price: ₹ 54,470.723
Antigen
E2F1
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q01094
Gene Symbols
E2F1
Immunogen
Between 300 and 350
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry
Conjugate
Unconjugated
Gene
E2F1
Gene Alias
E2F-1, RBAP1, RBBP3, RBP3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1869
Content And Storage
4° C
Form
Liquid
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- E2F1 is a member of the E2F family of transcription factors
- The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses
- The E2F proteins contain several evolutionally conserved domains found in most members of the family
- These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain
- This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain
- This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner
- It can mediate both cell proliferation and p53-dependent/independent apoptosis.