50-157-2314
TORC2 Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-157-2314-Each-of-1 | In Stock | ₹ 12,384.35 |
50-157-2314 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,384.35
GST (18%): ₹ 2,229.183
Total Price: ₹ 14,613.533
Antigen
TORC2
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q53ET0
Gene Symbols
CRTC2
Immunogen
Between 300 and 350
Quantity
10 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry
Conjugate
Unconjugated
Gene
CRTC2
Gene Alias
CREB-regulated transcription coactivator 2; OTTHUMP00000035255; TORC-2; transducer of CREB protein 2; transducer of regulated cAMP response element-binding protein (CREB) 2; transducer of regulated cAMP response element-binding protein 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
200186
Content And Storage
4° C
Form
Liquid
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Dog, Horse, Rabbit, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Chinese hamst CRTC2, also known as TORC2 (Transducers Of Regulated cAMP Response Element-Binding (CREB)) 2 and the related protein CRTC1 are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner via phosphorylation-dependent interactions
- Studies suggest that their phosphorylation and nuclear/cytoplasmic shuttling play an important role in the regulation of gluconeogenesis by cAMP
- CRTC2 is present in both B and T-lymphocytes and abundantly expressed in the thymus
- Its activity is important in regulating the expression of genes involved in cellular energy metabolism while CRTC1 is essential for energy balance and fertility.