50-157-2643
B7-H3/CD276 Recombinant Rabbit Monoclonal Antibody (BLR025F), Bethyl Laboratories
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-157-2643-Each-of-1 | In Stock | ₹ 48,474.74 |
50-157-2643 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,474.74
GST (18%): ₹ 8,725.453
Total Price: ₹ 57,200.193
Antigen
B7-H3/CD276
Classification
Recombinant Monoclonal
Conjugate
Unconjugated
Gene
CD276
Gene Alias
PSEC0249; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2; B7 homolog 3; CD276 antigen; costimulatory molecule; HB7H3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
80381
Content And Storage
4° C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
BLR025F
Formulation
BBS with 0.09% sodium azide; pH 8.2
Gene Accession No.
Q5ZPR3
Gene Symbols
CD276
Immunogen
between 484 to 534
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommende CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3
- CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma
- Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon
- In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing
- CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.