50-165-9620
CRYAB Mouse anti-Human, Clone: OTI2A1, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-165-9620-Each-of-1 | In Stock | ₹ 60,342.00 |
50-165-9620 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,342.00
GST (18%): ₹ 10,861.56
Total Price: ₹ 71,203.56
Antigen
CRYAB
Classification
Monoclonal
Conjugate
Unconjugated
Gene
CRYAB
Gene Alias
CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1410
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2A1
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
P02511
Gene Symbols
CRYAB
Immunogen
Full length human recombit protein of human CRYAB produced in HEK293T cell.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
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Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO Lens proteins consist almost entirely of crystallins (about 95%)
- Crystallins are also found vertebrate skeletal muscle tissue
- In the lens, their structural function is to assist in maintaining the proper refractive index of the lens
- The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma
- Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products-alpha-A and alpha-B
- There are at least 5 different proteins comprising the beta-crystallins
- The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens
- Alpha-Crystallin comprises 40% of total lens protein composition
- In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation
- It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintece
- Alpha-B crystallin has been linked to Alexander′s disease where it accumulates in brain cells of those afflicted.