50-166-5970
CD8A Mouse anti-Human, Clone: OTI7C10, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-5970-Each-of-1 | In Stock | ₹ 60,342.00 |
50-166-5970 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,342.00
GST (18%): ₹ 10,861.56
Total Price: ₹ 71,203.56
Antigen
CD8A
Classification
Monoclonal
Conjugate
Unconjugated
Gene
CD8A
Gene Alias
CD8, Leu2, MAL, p32
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
925
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI7C10
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
P01732
Gene Symbols
CD8A
Immunogen
Human recombit protein fragment corresponding to amino acids 22-182 of human CD8A produced in E.coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system
- The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules
- CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes
- The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells
- The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain
- Both alpha and beta chains share significant homology to immunoglobulin variable light chains
- The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer
- In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).