50-167-3452
VCAM1 Mouse anti-Canine, Human, Clone: OTI3H10, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-3452-Each-of-1 | In Stock | ₹ 44,954.79 |
50-167-3452 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,954.79
GST (18%): ₹ 8,091.862
Total Price: ₹ 53,046.652
Antigen
VCAM1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P19320, Q28260
Gene Symbols
VCAM1
Immunogen
Full length human recombit protein of human VCAM1 produced in HEK293T cell.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI3H10
Conjugate
Unconjugated
Gene
VCAM1
Gene Alias
CD106, INCAM-100
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
403982, 7412
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- VCAM-1 (vascular cell adhesion protein 1, CD106, INCAM-110) is a cell surface sialoglycoprotein expressed by cytokine activated endothelium
- VCAM-1 has a number of functions including the regulation of leukocyte migration, leukocyte-endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases
- VCAM-1 is distributed across non-leukocyte and leukocyte cells
- VCAM-1 expression is reportedly correlated with adhesion of melanoma, Burkitt lymphoma, osteosarcoma, and kidney carcinoma but not colon carcinoma cells to endothelial cells which may determine the site of tumor metastasis
- VCAM-1 is a member of the Ig superfamily of adhesion molecules, is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on unstimulated endothelial cells
- VCAM-1 is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages
- VCAM-1 serves as a ligand for leukocyte integrin alpha-beta (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium
- VCAM-1 plays a role in tumor metastasis, and may also be involved in the development of atherosclerosis and rheumatoid arthritis
- Two alternatively spliced transcripts encoding different isoforms of VCAM-1 have been described.