50-167-6215

CRYGC Monoclonal Antibody (OTI1D6), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-6215-Each-of-1 In Stock ₹ 44,954.79

50-167-6215 - Each of 1

₹ 44,954.79

In Stock

Quantity

1

Base Price: ₹ 44,954.79

GST (18%): ₹ 8,091.862

Total Price: ₹ 53,046.652

Antigen

CRYGC

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P07315

Gene Symbols

CRYGC

Immunogen

Full length human recombit protein of human CRYGC produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Western Blot

Clone

OTI1D6

Conjugate

Unconjugated

Gene

CRYGC

Gene Alias

CCL, CRYG3, CTRCT2

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1420

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous
  • The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens
  • Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins
  • Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily
  • Alpha and beta families are further divided into acidic and basic groups
  • Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions
  • Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions
  • They are differentially regulated after early development
  • Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster
  • Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.