50-167-6624

CDH3 Mouse anti-Human, Clone: OTI2D5, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-6624-Each-of-1 In Stock ₹ 44,954.79

50-167-6624 - Each of 1

₹ 44,954.79

In Stock

Quantity

1

Base Price: ₹ 44,954.79

GST (18%): ₹ 8,091.862

Total Price: ₹ 53,046.652

Antigen

CDH3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P22223

Gene Symbols

CDH3

Immunogen

Full length human recombit protein of human CDH3 produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2D5

Conjugate

Unconjugated

Gene

CDH3

Gene Alias

CDHP, HJMD, PCAD

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1001

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily
  • Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin
  • Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation
  • P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium
  • P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle
  • Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas
  • Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.