50-167-6679
TUBB2A Monoclonal Antibody (OTI3E6), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-6679-Each-of-1 | In Stock | ₹ 44,954.79 |
50-167-6679 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,954.79
GST (18%): ₹ 8,091.862
Total Price: ₹ 53,046.652
Antigen
TUBB2A
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q13885
Gene Symbols
TUBB2A
Immunogen
Full length human recombit protein of human TUBB2A produced in HEK293T cell.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI3E6
Conjugate
Unconjugated
Gene
TUBB2A
Gene Alias
CDCBM5, TUBB, TUBB2
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7280
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules
- Beta-III tubulin is primarily expressed in neurons and may be involved in neurogenesis, axon guidance and maintece
- Mutations in the beta tubulin gene are the cause of congenital fibrosis of the extraocular muscles type 3
- Beta-III tubulin was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues
- Glutamate residues at the C-terminus of beta III tubulin can be glutamylated
- The precise function of such modifications is unclear
- Tubulin is phosphorylated on Ser-172 by CDK1 during cell cycle progression
- Ser-172 phosphorylation inhibits tubulin incorporation into microtubules.Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55 kDa subunits: alpha and Beta
- Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton
- Because beta-tubulin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting.