50-167-6882

TOLLIP Monoclonal Antibody (OTI1D1), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-6882-Each-of-1 In Stock ₹ 44,954.79

50-167-6882 - Each of 1

₹ 44,954.79

In Stock

Quantity

1

Base Price: ₹ 44,954.79

GST (18%): ₹ 8,091.862

Total Price: ₹ 53,046.652

Antigen

TOLLIP

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q9H0E2

Gene Symbols

TOLLIP

Immunogen

Full length human recombit protein of human TOLLIP produced in HEK293T cell.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI1D1

Conjugate

Unconjugated

Gene

TOLLIP

Gene Alias

IL-1RAcPIP

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54472

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila
  • These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses
  • The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection
  • These adaptor molecules include TOLLIP, MyD88, and TRIF
  • TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation
  • This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.