50-167-7151

ACY1 Mouse anti-Human, Clone: OTI1E5, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-7151-Each-of-1 In Stock ₹ 46,061.06

50-167-7151 - Each of 1

₹ 46,061.06

In Stock

Quantity

1

Base Price: ₹ 46,061.06

GST (18%): ₹ 8,290.991

Total Price: ₹ 54,352.051

Antigen

ACY1

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with <5% trehalose and 0.05% sodium azide

Gene Accession No.

Q03154

Gene Symbols

ACY1

Immunogen

Full length human recombit protein of human ACY1 produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA

Clone

OTI1E5

Conjugate

Unconjugated

Gene

ACY1

Gene Alias

ACY-1, ACY1D, HEL-S-5

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

95

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • ACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids
  • This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors
  • The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes
  • Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids
  • Alternative splicing of this gene results in multiple transcript variants
  • Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene
  • A related pseudogene has been identified on chromosome 18.