50-168-2475
TRIM56 Mouse anti-Human, Clone: OTI8E12, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-2475-Each-of-1 | In Stock | ₹ 44,954.79 |
50-168-2475 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,954.79
GST (18%): ₹ 8,091.862
Total Price: ₹ 53,046.652
Antigen
TRIM56
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q9BRZ2
Gene Symbols
TRIM56
Immunogen
Human recombit protein fragment corresponding to amino acids 311-554 of human TRIM56 produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI8E12
Conjugate
Unconjugated
Gene
TRIM56
Gene Alias
RNF109
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
81844
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity
- In response to pathogen- and host-derived double-stranded DNA (dsDNA), targets TMEM173/STING to ′Lys-63′-linked ubiquitination, thereby promoting its homodimerization, a step required for the production of type I interferon IFN-beta Independently of its E3 ubiquitin ligase activity, positive regulator of TLR3 signaling
- Potentiates extracellular double stranded RNA (dsRNA)-induced expression of IFNB1 and interferon-stimulated genes ISG15, IFIT1/ISG56, CXCL10, OASL and CCL5/RANTES
- Promotes establishment of an antiviral state by TLR3 ligand and TLR3-mediated chemokine induction following infection by hepatitis C virus.