50-168-4482

PIN1 Monoclonal Antibody (OTI4H1), TrueMAB™, OriGene

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-168-4482-Each-of-1 In Stock ₹ 44,954.79

50-168-4482 - Each of 1

₹ 44,954.79

In Stock

Quantity

1

Base Price: ₹ 44,954.79

GST (18%): ₹ 8,091.862

Total Price: ₹ 53,046.652

Antigen

PIN1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q13526

Gene Symbols

PIN1

Immunogen

Full length human recombit protein of human PIN1 produced in E.coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI4H1

Conjugate

Unconjugated

Gene

PIN1

Gene Alias

DOD, UBL5

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

298696, 5300

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity
  • Displays a preference for an acidic residue N-terminal to the isomerized proline bond
  • Catalyzes pSer/Thr-Pro cis/trans isomerizations
  • Down-regulates kinase activity of BTK
  • Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation
  • Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation
  • Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.