50-168-4846
GFAP Mouse anti-Human, Rat, Clone: UMAB5, lyophilized, UltraMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-4846-Each-of-1 | In Stock | ₹ 65,489.76 |
50-168-4846 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 65,489.76
GST (18%): ₹ 11,788.157
Total Price: ₹ 77,277.917
Antigen
GFAP
Classification
Monoclonal
Conjugate
Unconjugated
Gene
GFAP
Gene Alias
ALXDRD
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
24387, 2670
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
UMAB5
Formulation
PBS with 8% trehalose and no preservative
Gene Accession No.
P14136, P47819
Gene Symbols
Gfap
Immunogen
Full length human recombit protein of human GFAP produced in HEK293T cell.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG1
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Description
- GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family
- GFAP is heavily, and specifically, expressed in astrocytes and certain astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves
- In addition, neural stem cells strongly express GFAP
- Antibodies to GFAP are very useful as markers of astrocytic cells
- In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP
- GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes
- GFAP is used as a marker to distinguish astrocytes from other glial cells during development
- Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system
- Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.