50-172-6194

PLK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-172-6194-Each-of-1 In Stock ₹ 44,150.23

50-172-6194 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

PLK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PLK1

Gene Alias

PLK, PLK 1, PLK1, Polo like kinase 1, STPK13

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18817, 25515, 5347

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.16 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

P53350, Q07832, Q62673

Gene Symbols

Plk1

Immunogen

PLK1 Fusion Protein Ag0284

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PLK1 is a Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis
  • Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains
  • Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55, ECT2, ERCC6L, FBXO5/EMI1, FOXM1, KIF20A/MKLP2, CENPU, NEDD1, NINL, NPM1, NUDC, PKMYT1/MYT1, KIZ, PPP1R12A/MYPT1, PRC1, RACGAP1/CYK4, SGOL1, STAG2/SA2, TEX14, TOPORS, p73/TP73, TPT1 and WEE1
  • Plays a key role in centrosome functions and the assembly of bipolar spindles by phosphorylating KIZ, NEDD1 and NINL.