50-172-6765
PICK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-6765-Each-of-1 | In Stock | ₹ 44,150.23 |
50-172-6765 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
PICK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PICK1
Gene Alias
PICK, PICK1, PRKCA binding protein, PRKCABP
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18693, 84591, 9463
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.13 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
Q62083, Q9EP80, Q9NRD5
Gene Symbols
Pick1
Immunogen
PICK1 Fusion Protein Ag1443
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PSD-95/DLG/ZO-1 (PDZ) domain-containing proteins play a central role in synaptic membrane protein localization
- The protein interacting with protein kinase C (PICK1) is a synaptic PDZ domain protein that also contains a coiled-coil and acidic domain
- Studies indicate that PICK1 functions as a targeting and transport protein and has been shown to interact with protein kinase C alpha (PKCalpha), AMPA-type glutamate receptors, and several other membrane receptors via its PDZ domain
- The interaction of PICK1 with PKCalpha is highly dependent on the activation of the kinase
- It appears that PICK1 directs the activated form of PKCalpha to membrane anchored GluR2
- Once phosphorylated by PKCalpha, GluR2 is released from the synaptic anchor proteins
- Once released, GluR2 is transported from the synaptic membrane in a PICK1-dependent manner.