50-172-7351

CPI17 Rabbit anti-Human, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-172-7351-Each-of-1 In Stock ₹ 44,150.23

50-172-7351 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

CPI17

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PPP1R14A

Gene Alias

CPI 17, CPI17, PPP1INL, PPP1R14A

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

94274

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Western Blot

Concentration

0.13 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.3

Gene Accession No.

Q96A00

Gene Symbols

PPP1R14A

Immunogen

CPI17 Fusion Protein Ag2237

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • CPI-17 is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate
  • CPI-17 was originally identified as a PKC-potentiated inhibitory protein of protein phosphatase-1, which is domitly expressed in smooth muscle
  • Phosphorylation at Threonine 38, in vitro, by PKC or Rho-kinase enhances the inhibitory potency toward myosin phosphatase
  • CPI-17 is also phosphorylated at Threonine 38 by protein kinase N and might be involved in the calcium sensitization of smooth muscle contraction as a downstream effector of Rho and/or arachidonic acid
  • CPI-17 is dually phosphorylated at Serine 12 and Threonine 38 by a MYPT-associated kinase, M110 kinase.