50-172-7389
CDK9 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-7389-Each-of-1 | In Stock | ₹ 44,150.23 |
50-172-7389 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
CDK9
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDK9
Gene Alias
C 2k, CDC2L4, CDK9, Cell division protein kinase 9, CTK1, cyclin dependent kinase 9, PITALRE, TAK
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1025, 107951, 362110
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.4 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
P50750, Q641Z4, Q99J95
Gene Symbols
Cdk9
Immunogen
CDK9 Fusion Protein Ag2318
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- CDK9 (cyclin-dependent kinase 9) is a member of the cyclin-dependent protein kinase family
- It is involved in the regulation of transcription
- CDK9 is a member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex
- This complex facilitates the transition from abortive to productive elongation by phosphorylating the CTD of the large subunit of RNA polymerase II, POLR2A, SUPT5H, and RDBP
- The complex is inactive when in the 7SK snRNP complex form
- CDK9 phosphorylates EP300, MYOD1, RPB1/POLR2A, AR, DSIF, and NELF
- It regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors
- CDK9 promotes RNA synthesis in genetic programs for cell growth, differentiation, and viral pathogenesis
- The CDK9/cyclin-K complex also has kinase activity towards CTD of RNAPII and can substitute for CDK9/cyclin-T P-TEFb in vitro
- Chronic activation of CDK9 causes cardic myocyte enlargement leading to cardiac hypertrophy and confers a predisposition to heart failure.