50-172-7786
UCN2 Rabbit anti-Human, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-172-7786-Each-of-1 | In Stock | ₹ 44,150.23 |
50-172-7786 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
UCN2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
UCN2
Gene Alias
SRP, Stresscopin related peptide, UCN II, UCN2, UCNI, UR, urocortin 2, Urocortin II, Urocortin related peptide, URP
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
90226
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
0.37 mg/mL
Formulation
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.
Q96RP3
Gene Symbols
UCN2
Immunogen
UCN2 Fusion Protein Ag2836
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Two major regulatory peptides were originally isolated from fish urophysial extracts, Urotensin I and II
- In both frog and human, the Urotensin II sequence is located at the carboxy-terminal position of the precursor
- Human Urotensin II is composed of only 11 amino acid residues, while fish and frog Urotensin II possess 12 and 13 amino acid residues, respectively
- The cyclic region of Urotensin II, which is responsible for the biological activity of the peptide, has been fully conserved from fish to human
- However, several substitutions have occurred in the amino-terminal region of the molecule
- A human G protein-coupled receptor, GPR14, is the Urotensin II receptor
- Human Urotensin II is found within both vascular and cardiac tissue, including coronary atheroma, and effectively constricts isolated arteries from nonhuman primates
- Urotensin II may act as an autocrine and/or paracrine hormone rather than as a circulating hormone, by playing an important role in the development of ventricular hypertrophy induced by chronic hypoxia.