50-173-0139
PDXK Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-0139-Each-of-1 | In Stock | ₹ 44,150.23 |
50-173-0139 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
PDXK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PDXK
Gene Alias
C21orf124, C21orf97, PDXK, PKH, PNK, PRED79, Pyridoxal kinase, Pyridoxine kinase
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
216134, 83578, 8566
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.33 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O00764, O35331, Q8K183
Gene Symbols
PDXK
Immunogen
PDXK Fusion Protein Ag7451
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters
- The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity
- Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested
- The expression of PDXK shows circadian oscillations
- The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian oscillations in expression
- Mice devoid of all 3 transcription factors show decreased levels of brain PLP, serotonin, and dopamine, and are highly susceptible to frequently lethal generalized spontaneous and audiogenic epilepsies.