50-173-0757
CCR2a Rabbit anti-Human, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-0757-Each-of-1 | In Stock | ₹ 44,150.23 |
50-173-0757 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
CCR2a
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CCR2
Gene Alias
C C chemokine receptor type 2, C C CKR 2, CC CKR 2, CCR 2, CCR2, CCR2a, CCR2b, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP 1 R
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
729230
Content And Storage
-20°C
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.37 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P41597
Gene Symbols
CCR2
Immunogen
Peptide
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody 16153-1-AP is raised against the peptide of 344-358 amino acids of CCR2a
- It is specific to CCR2a
- CCR2, a chemokine receptor, is a regulator of monocyte/macrophage trafficking and is upregulated in response to inflammation
- Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms
- The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages
- Activation of monocytes by MCP-1 may mediate the monocytic infiltration of tissues in atherosclerosis and other inflammatory disorders including rheumatoid arthritis, alveolitis, and tumor infiltration
- Two isoforms are produced by alternative splicing
- CCR2 has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen, thymus, and vessel
- Increased expression of CCR2 has been documented in CD3+ lymphocytes in rheumatoid arthritis
- ESTs have been isolated from liver/spleen and prostate libraries.