50-173-0818

WRNIP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-0818-Each-of-1 In Stock ₹ 44,150.23

50-173-0818 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

WRNIP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

WRNIP1

Gene Alias

ATPase WRNIP1, RP11 420G6.2, WHIP, WRNIP1

Host Species

Rabbit

Purification Method

Antigen Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

282835, 56897, 78903

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

0.38 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8CG07, Q91XU0, Q96S55

Gene Symbols

Wrnip1

Immunogen

WRNIP1 Fusion Protein Ag9040

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Werner′s syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN)
  • The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein
  • This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus
  • It has sequence similarity to replication factor C family proteins and is conserved from E
  • coli to human
  • This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis
  • This protein also interacts with nucleoporins at nuclear pore complexes
  • Two transcript variants encoding different isoforms have been isolated for this gene.