50-173-1151
TBX3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-173-1151-Each-of-1 | In Stock | ₹ 44,150.23 |
50-173-1151 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,150.23
GST (18%): ₹ 7,947.041
Total Price: ₹ 52,097.271
Antigen
TBX3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TBX3
Gene Alias
T box 3, T box protein 3, TBX3, TBX3 ISO, UMS, XHL
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21386, 353305, 6926
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
0.27 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O15119, P70324, Q7TST9
Gene Symbols
Tbx3
Immunogen
TBX3 Fusion Protein Ag9955
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- T-box 3 (TBX3) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box
- T-box genes encode transcription factors involved in the regulation of developmental processes
- The Tbx3 protein is a transcriptional repressor that binds the canonical Brachychury bindig sites, and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb
- Tbx3 is required for normal mammary development and is also implicated in tumor development
- Tbx3 expression also increases during osteoblast differentiation, and may function as a determit of osteoblast cell numbers
- Mutations in T-box 3 cause ulnar-mammary syndrome (MIM 181450), affecting limb, apocrine gland, tooth, hair, and genital development
- Alternative splicing results in three transcript variants encoding different isoforms; however, the nature of one full length variant has not been determined
- Subsets of human breast cancer cell lines overexpress TBX36
- in vitro, Tbx3 overexpression in mouse embryo fibroblasts leads to immortalization of cells
- Truncated forms of Tbx3 are increased in plasma samples.