50-173-6690

CD1d Mouse anti-Human, Clone: 1C12F1, Proteintech

Manufacturer: Proteintech Group Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-173-6690-Each-of-1 In Stock ₹ 44,150.23

50-173-6690 - Each of 1

₹ 44,150.23

In Stock

Quantity

1

Base Price: ₹ 44,150.23

GST (18%): ₹ 7,947.041

Total Price: ₹ 52,097.271

Antigen

CD1d

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P15813

Gene Symbols

CD1D

Immunogen

CD1d Fusion Protein Ag11108

Quantity

150 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

1C12F1

Conjugate

Unconjugated

Gene

CD1D

Gene Alias

CD1A, CD1D, CD1d molecule, R3, R3G1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

912

Content And Storage

-20°C

Form

Liquid

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Description

  • CD1d is a 49 kDa heavy chain associated with Beta 2 microglobulin on cortical thymocytes
  • Beta 2 microglobulin independent expression of CD1d has also been demonstrated on human intestinal epithelial cells
  • CD1d is the sole group 2 member of the CD1 family of major histocompatibility (MHC) like glycoproteins
  • The CD1d gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin
  • The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells
  • The human genome contains five CD1 family genes organized in a cluster on chromosome 1
  • The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands
  • The protein encoded by the CD1d gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail
  • Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease.