50-194-3858

VDAC/PorinRabbit anti-Bovine, Goat, Human, Mouse, Porcine, Rat, Polyclonal, Rockland™

Manufacturer: Rockland Immunochemicals

Select a Size

Pack Size SKU Availability Price
Each of 1 50-194-3858-Each-of-1 In Stock ₹ 43,898.36

50-194-3858 - Each of 1

₹ 43,898.36

In Stock

Quantity

1

Base Price: ₹ 43,898.36

GST (18%): ₹ 7,901.705

Total Price: ₹ 51,800.065

Antigen

VDAC/Porin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

VDAC1

Gene Alias

AL033343; hVDAC1; MGC111064; Mitochondrial outer membrane protein porin 1; Mitochondrial Porin; mVDAC1; mVDAC5; N2441; OMP2; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; POR1; PORIN; Porin 31HL; Porin 31HM; porin POR1; PORIN-31-HL; rVDAC1; VD; VDAC; Vdac1; VDAC-1; Vdac5; VDAC-5; voltage dependent anion channel 1; voltage-dependent anion channel 1; Voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 5; YNL055C; YNL2441C

Host Species

Rabbit

Regulatory Status

RUO

Gene ID (Entrez)

102173290, 22333, 282119, 397010, 7416, 83529

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

P21796, P45879, Q60932, Q9MZ16, Q9Z2L0

Gene Symbols

VDAC1

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Bovine, Goat, Human, Mouse, Porcine, Rat

Product Type

Antibody

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Anti-VDAC/Porin Antibody is directed against human VDAC1/Porin1 protein
  • A BLAST analysis was used to suggest that this antibody would react with VDAC1/Porin1 from a wide range or organisms, including avian, mammalian, aquatic and reptilian sources based on 100% homology for the immunogen sequence
  • Cross reactivity will occur with all forms of VDACs including VDAC1, VDAC2 (4 isoforms) and VDAC3 (2 isoforms)
  • Such broad reactivity makes this antibody useful as an excellent loading control (mitochondrial)
  • Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins
  • It was discovered in the mitochondrial outer membrane
  • It also is expressed in the plasma membrane
  • At least three different VDAC genes have been identified in vertebrates
  • VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis
  • For example, VDAC constitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria
  • And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.