mTORRabbit anti-Human, Mouse, Rat, Polyclonal, Rockland™
Manufacturer: Rockland Immunochemicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-194-3860-Each-of-1 | In Stock | ₹ 52,930.08 |
50-194-3860 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,930.08
GST (18%): ₹ 9,527.414
Total Price: ₹ 62,457.494
Antigen
mTOR
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MTOR
Gene Alias
2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; Frap; FRAP1; FRAP2; Mammalian target of rapamycin; Mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; Rapamycin target protein 1; RAPT1; Serine/threonine-protein kinase mTOR; SKS
Host Species
Rabbit
Regulatory Status
RUO
Gene ID (Entrez)
2475, 56717, 56718
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunoprecipitation, Western Blot
Concentration
0.9 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
P42345, P42346, Q9JLN9
Gene Symbols
MTOR
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Reactivity occurs with both phosphorylated and non-phosphorylated forms of mTOR at S2448 from human derived tissues and cells
- A BLAST analysis was used to suggest cross reactivity with mTOR protein from rat and mouse based on 100% homology with the immunizing sequence
- Expect partial reactivity against mTOR homologues from zebrafish (94%) and dog (89%)
- Reactivity against homologues from other sources is not known
- Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis
- mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation
- A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation
- Mutations affecting the gene results in Smith-Kingsmore syndrome.