PI3K p85 Mouse anti-Human, Clone: 5C11, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-197-9941-Each-of-1 | In Stock | ₹ 47,267.90 |
50-197-9941 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,267.90
GST (18%): ₹ 8,508.222
Total Price: ₹ 55,776.122
Antigen
PI3K p85
Classification
Monoclonal
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
O00459, P27986
Gene Symbols
PIK3R1, PIK3R2
Immunogen
Recombinant mouse PI3K p85 Protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
5C11
Conjugate
Unconjugated
Gene
PIK3R2
Gene Alias
AGM7; GRB1; IMD36; MPPH; MPPH1; p50alpha; p55alpha; p85; p85alpha; p85-ALPHA; P85B; p85beta; p85-BETA; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; phosphatidylinositol 3-kinase regulartory subunit polypeptide 2; Phosphatidylinositol 3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosphatidylinositol 3-kinase-associated p-85 alpha; Phosphoinositide 3-kinase p85 (other splicing variants: p55 and p50); Phosphoinositide 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphoinositide-3-kinase regulatory subunit; phosphoinositide-3-kinase regulatory subunit 1; phosphoinositide-3-kinase regulatory subunit 2; phosphoinositide-3-kinase regulatory subunit alpha; phosphoinositide-3-kinase regulatory subunit beta; phosphoinositide-3-kinase, regulatory subunit 1 (alpha); phosphoinositide-3-kinase, regulatory subunit 2 (beta); PI3K; PI3K regulatory subunit alpha; PI3K regulatory subunit beta; PI3KA; PI3-kinase p85 subunit alpha; PI3-kinase p85 subunit beta; PI3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-alpha; PI3-kinase subunit p85-beta; Pik3r1; PIK3R2; ptdIns-3-kinase p85-alpha; ptdIns-3-kinase p85-beta; ptdIns-3-kinase regulatory subunit alpha; ptdIns-3-kinase regulatory subunit beta; ptdIns-3-kinase regulatory subunit p85-alpha; ptdIns-3-kinase regulatory subunit p85-beta
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
5295, 5296
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Phosphatidylinositol 3-kinase (PIK3) is a signaling protein that phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position
- Signaling is initiated when upstream tyrosine kinase receptors or G protein coupled receptors are bound by their ligands
- It binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane
- Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance
- During insulin stimulation, it also binds to IRS-1
- Mutations in the gene can result in Agammaglobulinemia 7, SHORT syndrome, or Immunodeficiency 36.