50-198-1664
PON3 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-1664-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-1664 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
PON3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PON3
Gene Alias
2810004E20; AI786302; arylesterase 3; BOS_4015; paraoxanase-3; paraoxonase 3; PON3; Serum paraoxonase/lactonase 3
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5446
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q15166
Gene Symbols
PON3
Immunogen
KLH conjugated synthetic peptide derived from human PON3.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
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Description
- Paraoxonase-1 (PON1) is a calcium-dependent ester hydrolase that is tightly associated with apoA-I in HDL
- PON1 prevents the oxidation of LDL, thereby the formation of atherogenic oxidised-LDL
- Polymorphisms of the human PON1 gene are correlated with coronary artery disease, indicating a genetic association between PON1 and coronary artery disease
- PON1 activity is lower in subjects prone to development of atherosclerosis such as in type 1 and type 2 diabetes, familial hypercholesterolemia, and renal disease, indicating the involvement of PON1 in atherosclerosis development
- PON2 is a ubiquitously expressed intracellular protein that can protect cells against oxidative damage
- PON3 is similar to PON1 in activity but differs from it in substrate specificity
- PON1 and PON3 are implicated in lowering the risk of developing coronary artery disease and atherosclerosis
- Human PON3 protein shares the 3 conserved cysteine residues identified in PON1, suggesting their importance of in vivo activities
- PON1-based catalytic scavengers can be a way to safe and effective organophosphate intoxication.