GABRA6/GABA A Receptor alpha 6 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-1914-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-1914 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
GABRA6/GABA A Receptor alpha 6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Gabra6
Gene Alias
alpha6; GABA subunit A receptor alpha 6; GABA(A) receptor subunit alpha-6; GABA(A) receptor, alpha 6; GABA-A receptor alpha-6 subunit; GABAAR alpha6; GABA-ARalpha6; GABRA 6; GABRA6; Gabra-6; gamma-aminobutyric acid A receptor, alpha 6; gamma-aminobutyric acid (GABA) A receptor, alpha 6; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6; gamma-aminobutyric acid A receptor, alpha 6; Gamma-aminobutyric acid receptor subunit alpha-6; gamma-aminobutyric acid type A receptor alpha6 subunit; subunit alpha 6 gamma-aminobutyric acid (GABA-A) receptor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2559
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q16445
Gene Symbols
Gabra6
Immunogen
KLH conjugated synthetic peptide derived from human GABRA6/GABA A Receptor alpha 6.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABA-A Receptor (GABA-A R) Subtype
- GABA-A Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse
- The GABA-A R is a multimeric subunit complex
- To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified
- Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABA-A Rs sensitive to GABA
- However, coexpression of a gamma-subunit is required for benzodiazepine modulation
- The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor
- Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABA-A R function.