50-198-2220
Phospho-SP1 (Thr453) Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2220-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-2220 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-SP1 (Thr453)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SP1
Gene Alias
1110003E12Rik; AA450830; AI845540; HGNC:11205; Sp1; Sp1 transcription factor; Sp1-1; Specificity protein 1; trans-acting transcription factor 1; Transcription factor Sp1; TSFP1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6667
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P08047
Gene Symbols
SP1
Immunogen
KLH conjugated synthetic phosphopeptide derived from human TSFP1 around the phosphorylation site of Thr453.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli
- Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses
- Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation)
- Binds also the PDGFR-alpha G-box promoter
- May have a role in modulating the cellular response to DNA damage
- Implicated in chromatin remodeling
- Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter
- Plays an essential role in the regulation of FE65 gene expression.