50-198-2563
Phospho-Dynamin 1 (Ser774) Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2563-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-2563 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
Phospho-Dynamin 1 (Ser774)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DNM1
Gene Alias
AI838169; B-dynamin; BOS_12077; D100; DNM; Dnm1; Dyn1; dynamin 1; Dynamin BREDNM19; Dynamin, brain; Dynamin1; Dynamin-1; EC 3.6.5.5; EIEE31; Ftfl; Kiaa4093; mKIAA4093; Neuronal dynamin; OTTHUMP00000215500
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1759
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q05193
Gene Symbols
DNM1
Immunogen
KLH conjugated synthetic phosphopeptide derived from human Dynamin 1 around the phosphorylation site of Ser774.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Dynamin is a GTPase required for endocytosis of clathrin coated vesicles from the membrane
- Dynamin′s involvement in endocytosis was first discovered during the characterization of the temperature sensitive parylytic shibire mutation from Drosophila melanogaster
- Three closely related isoforms have been identified in mammals
- Dynamin1 is expressed exclusively in neurons, dynamin2 is ubiquitously expressed and dynamin3 is expressed primarily in the testes
- Each of these isoforms of dynamin also has several splice variants
- This suggests that each isoform/splice variant may have separate intracellular targets or function in the budding of distinct vesicle types
- Common domain features of the dynamin proteins include an amino acid terminal GTPase domain, a central pleckstrin homology domain and a highly basic proline rich carboxyl terminus with several Src homology 3 (SH3) domains
- These SH3 domains target the dynamin to the clathrin coated pit
- Dynamin is known to interact with at least two proteins, AP2 adaptor protein complex and amphiphysin.