50-198-2603
XAF1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2603-Each-of-1 | In Stock | ₹ 38,381.25 |
50-198-2603 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,381.25
GST (18%): ₹ 6,908.625
Total Price: ₹ 45,289.875
Antigen
XAF1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
XAF1
Gene Alias
BIRC4 binding protein; BIRC4-binding protein; Birc4bp; F-box protein 39; Fbox39; HSXIAPAF1; novel TRAF-type zinc finger protein; Xaf1; XIAP associated factor 1; XIAPAF1; XIAP-associated factor 1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
54739
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q6GPH4
Gene Symbols
XAF1
Immunogen
KLH conjugated synthetic peptide derived from mouse XAF1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The inhibitors of apoptosis (IAP) proteins prevent cell death both in vitro and in vivo by virtue of inhibition of distinct caspases
- The X-linked Inhibitor of Apoptosis, XIAP, is a key member of the IAP family of proteins
- The caspase inhibiting activity of XIAP is negatively regulated by at least two XIAP-interacting proteins, XIAP-associated factor 1 (XAF1) and Smac/DIABLO
- XAF1 binds to XIAP and antagonizes caspase inhibitory activities of XIAP
- Expression of XAF1 triggers a redistribution of XIAP from the cytosol to the nucleus
- XAF1 is ubiquitously expressed in normal tissues, but is present at low or undetectable levels in many different cancer cell lines.